Apexion Health Sermorelin treatment vial
LONGEVITYPEPTIDE

MONTHLY SUPPLY · 0.2MG–0.3MG/DAY

SERMORELIN

TREATMENT

Stimulate natural growth hormone production

SUPPORT

Sermorelin is a growth hormone-releasing hormone analogue that signals the pituitary to produce GH naturally — sustaining the body's own feedback mechanisms rather than bypassing them.

Shop Now

Lab-Tested · Physician-Supervised · Discreet Delivery

Apexion Health — LONGEVITY

GROWTH HORMONE, PRODUCED BY YOUR OWN PITUITARY.

Sermorelin is a 29-amino-acid analogue of growth hormone-releasing hormone (GHRH). Rather than supplying exogenous GH, it signals the pituitary to produce and release it naturally — preserving the body's own feedback mechanisms. GH levels decline steadily after age 30, contributing to reduced lean mass, slower recovery, and changes in body composition.

Clinical Benefits

SERMORELIN SUPPORTS YOUR HEALTH AT THE CELLULAR LEVEL

  1. 01.

    STIMULATES THE PITUITARY TO INCREASE NATURAL GH OUTPUT

  2. 02.

    SUPPORTS LEAN BODY COMPOSITION AND FAT METABOLISM

  3. 03.

    IMPROVES DEEP SLEEP QUALITY AND OVERNIGHT RECOVERY

  4. 04.

    ENHANCES PHYSICAL PERFORMANCE AND STAMINA

  5. 05.

    PRESERVES NATURAL PITUITARY FEEDBACK MECHANISMS

  6. 06.

    PHYSICIAN-SUPERVISED WITH GRADUAL DOSE TITRATION

Shop Now

Clinical Evidence

How It Works in the Body

01 — Dose & Efficacy

GH Axis Stimulation

GH Pulse Amplitude Restored pulsatile secretion50%
Lean Body Mass Modest increase in studies15%
Sleep Quality Improved in patient reports40%

Walker et al., JCEM 1994; Khorram et al., J Anti-Aging Med 2000

02 — Hormone Panel

Hormonal Axis Response

MarkerWithoutWith Treatment
IGF-1ng/mL
140
190+50
GH Peak (stim)ng/mL
3.5
7.0+100%
Body Fat (est.)%
28
26−2%
Lean Mass (est.)kg
55
57+2

Preserves endogenous GH physiology

Unlike exogenous rhGH, sermorelin preserves pulsatile GH secretion and the negative feedback loop. This reduces IGF-1 overshoot risk. Large-scale RCT data is limited.

Walker et al., JCEM 1994; Corpas et al., Endocrine Reviews 1993

03 — Protocol

Sermorelin Protocol

BaselinePre-treatment
  • ›IGF-1 level (age-adjusted)
  • ›GH stimulation test
  • ›Body composition (DEXA)
InitiationMonths 1–3
  • ›0.2–0.3 mg SC nightly
  • ›IGF-1 at 1 month
  • ›Tolerability & sleep quality
OptimizationMonths 4+
  • ›Titrate to target IGF-1 range
  • ›Body composition q6 months
  • ›IGF-1 & metabolic q3–6 months

Nightly injection required (t½ ~12 min)

Inject SC every night before bed (1–2 hrs after last meal). Titrate to upper half of age-adjusted IGF-1 range. Evidence limited — counsel accordingly.

All protocols physician-supervised and adjusted per individual labs.